And Diabetes Glut4
Glut4 Is Reduced In Slow Muscle Fibers Of Type 2 Diabetes Muscle Groupspecific Regulation Of Glut 4 Glucose The impact of diabetes and insulin therapy on glut 4 expression also varied as a function of muscle group. after four weeks of diabetes, glut 4 levels were reduced by approximately 50% in cardiac muscle, soleus, and gastrocnemius. in contrast, glut 4 content in rectus abdominis and vastus lateralis was similar to that in control rats. Exercise, glut4, and skeletal muscle glucose uptake glucose is an important fuel for contracting muscle, and normal glucose metabolism is vital for health. glucose enters the muscle cell via facilitated diffusion through the glut4 glucose transporter which translocates from intracellular storage depots to the plasma m. Total glut4 content in skeletal muscle from individuals with type 2 diabetes is normal; however, recent studies have demonstrated that translocation of glut4 to the plasma membrane is decreased in and diabetes glut4 response to i...